You have just finished your experiment, written down the results, and now it's time to clean up. J. Nucl. Overcoming the complexity and difficulty of selenides (R-Se-R) and/or multiselenides (R-Se n-R; n 2), we aimed to optimize the reaction condition for the tolerable preparation of sodium selenide (Na 2 Se) by reducing Se with NaBH 4, and then to achieve selective syntheses of dialkyl selenides 1 by . She holds teaching certifications in mathematics, biology and general science. The solution spits near the end and you get fewer crystals. Sodium hydroxide solution, 0.4 M (IRRITANT), about 100 cm, Dilute hydrochloric acid, 0.4 M, about 100 cm, Methyl orange indicator solution (or alternative) in small dropper bottle. The reaction between hydrochloric acid and sodium hydroxide is below. For e, n=3 biological replicates; error bars are S.D. Suzuki, K. T. & Ogra, Y. Metabolic pathway for selenium in the body: speciation by HPLC-ICP MS with enriched Se. As we can see, the result of the interaction of two highly aggressive compounds is table salt and water - compounds that are ultimately harmless, even beneficial, to human beings. By the physical state of substances, it is homogenous. This chemistry video explains how to write the balanced molecular equation and the net ionic equation of the reaction between Sodium Carbonate and Hydrochlor. To obtain Sodium hydroselenide can be made by reducing selenium with sodium borohydride: Alternatively it can be made from sodium ethoxide exposed to hydrogen selenide:[1]. In other words, the wedding ceremony took place in a warm, friendly, and loving atmosphere. For all panels, *p<0.05, **p<0.01, and ***p<0.001 (students two-tailed t test). Values are relative to cells cultured under normoxic condition (20% O2), set at 1.0. b, Viability of non-transformed (blue bars) and selenophilic cancer (red bars) cells under nutrient starved conditions (10% or 20% growth media) for 48hr. Donating to our cause, you are not only help supporting this website going on, but also Selenite, the ion Selenous acid Sodium selenite +6 compounds +6 compounds can exist in anions or cations, too. Therefore, it is classified as a hazardous waste and must be disposed of properly. One of the most widespread alkalis, also known as causticsoda. Source data are provided with this paper. Values are relative to each untreated cells (=1.0). Additionally, carbon dioxide is also formed. (2017) GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition. succeed. Hum. f, Viability of U251 cells treated with vehicle, 12M sodium selenite, and/or 10M Erastin for 72hr. Students need training in using burettes correctly, including how to clamp them securely and fill them safely. It is an induced solubility, as it were, That's right -- the new compound doesn't revert to the sodium salt after accepting the proton. Google Scholar. [3] Alternatively, sodium selenide can be prepared by the reaction of gaseous hydrogen selenide with metallic sodium at 100 C. To learn more, see our tips on writing great answers. And water is one of the products of ourreaction. 2a Determination of the reacting volumes of solutions of a strong acid and a strong alkali by titration. Electronic configuration. What video game is Charlie playing in Poker Face S01E07? What are the chemical and physical characteristic of H2Se (Sodium selenide; Selenodisodium; Disodio selenide)? Did any DOS compatibility layers exist for any UNIX-like systems before DOS started to become outmoded? Talanta 153, 306331 (2016). The compound reacts with electrophiles to produce the selenium compounds. In other words, the number of substances entering into the reaction is equal to the number of substances received as a result of the reaction. You can thus say that in this chemical reaction, two substances react. Biophys. Calculated pH values of common acids and bases for 1, 10, and 100 mmol/L (valid for standard conditions at 25, 1 atm; acidity constants are taken from here ): other reactions: Free software ( Example) Demo: Online pH-Calculator. Sanjana, N. E., Shalem, O. Hydrochloric acid (HCl), a strong acid, is composed of a single hydrogen atom and a single chlorine atom bonded together covalently. e, shows a nonhypoxic region (as indicated by only background nonspecific stain in CA9) with a high Ki67 index. Sodium metal reacts with hydrochloric acid to produce salt and hydrogen gas. Breast and other cancer cells are selenophilic, owing to a secondary function of the cystine/glutamate antiporter SLC7A11 that promotes selenium uptake and selenocysteine biosynthesis, which, by allowing production of selenoproteins such as GPX4, protects cells against ferroptosis. and N.L. top. Nucleic Acids Res, 10.1093/nar/gkx247). And in combination, our reaction products can be found at home in soup, brine, or salt water. The X-axis and y-axis of Flow cytometry density plots were designated as Annexin V-FITC and PI, respectively. b, Validation of specificity of GPX4 antibody in CTRL and SEPHS2 KO MDAMB231 cell pellet block by immunohistochemistry. ISEB Common Entrance Exam at 13+ Science: Study Guide & Test Prep, Psychological Research & Experimental Design, All Teacher Certification Test Prep Courses, Calculations of Hydrochloric Acid and Sodium Hydroxide, Process of Neutralizing Hydrochloric Acid, Physical & Chemical Properties of Elements: Metals, Nonmetals & Metalloids, Neutralizing Solutions with Sodium Hydroxide, ISEB Common Entrance Exam at 13+ Science Flashcards, UExcel Anatomy & Physiology: Study Guide & Test Prep, UExcel Microbiology: Study Guide & Test Prep, Human Anatomy & Physiology: Help and Review, NY Regents Exam - Earth Science: Help and Review, NY Regents Exam - Chemistry: Tutoring Solution, NY Regents Exam - Living Environment: Tutoring Solution, NY Regents Exam - Physics: Tutoring Solution, SAT Subject Test Chemistry: Tutoring Solution, SAT Subject Test Physics: Tutoring Solution, What is Sodium Hydroxide? If you simply dump it down the drain, the acid could do a lot of damage to the pipes and kill the microbes necessary to breakdown organic matter in the sewage. As a member, you'll also get unlimited access to over 88,000 Sodium selenite usually is prepared by the reaction of selenium dioxide with sodium hydroxide:[1]. Enrolling in a course lets you earn progress by passing quizzes and exams. directly helping charity project in Vietnam building shcools in rural areas. The reaction between hydrochloric acid and sodium hydroxide is below. lessons in math, English, science, history, and more. Doll, S. et al. This website uses cookies and similar technologies to deliver its services, to analyse and improve performance and to provide personalised content and advertising. Values are relative to the cells treated with vehicle (=1.0). These authors contributed equally: Anne E. Carlisle, Namgyu Lee. Middle School Earth Science: Help and Review, 6th Grade Life Science: Enrichment Program, 7th Grade Life Science: Enrichment Program, 8th Grade Life Science: Enrichment Program, ILTS Science - Chemistry (106): Test Practice and Study Guide, CSET Science Subtest II Chemistry (218): Practice & Study Guide, UExcel Earth Science: Study Guide & Test Prep, DSST Health & Human Development: Study Guide & Test Prep, AP Environmental Science: Help and Review, Prentice Hall Biology: Online Textbook Help, Prentice Hall Earth Science: Online Textbook Help, Middle School Physical Science: Help and Review, Middle School Physical Science: Homework Help Resource, Create an account to start this course today. Publishers note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This should produce a white crystalline solid in one or two days. 1. p. 432. 24 chapters | Spallholz, J. E. On the nature of selenium toxicity and carcinostatic activity. However, reaction of 1,3-butadiene with selenium oxide in the presence of concentrated HCl yielded 1,1,3,4-tetrachloroselanolane, which on dechlorination with K 2 S 2 O 5 produced 3,4-dichloroselenolane. Proc. Breast Cancer Res. For all panels, the measure of center is mean. The reaction produces a harmless substance, salt water. ), Use a pipette with pipette filler to transfer 25 (or 20) cm. Extended Data Fig. The reaction was inhibited by mannitol, a hydroxyl radical quencher, but not by superoxide dismutase or catalase, strongly suggesting the involvement of hydroxyl radicals and ruling out participations of superoxide anions or hydrogen peroxide. sodium metal, Na(s) hydrochloric acid, HCl(aq) and two substances are produced salt, i.e. Via a reaction between an acid and an alkali, we have turned the saddest of tragedies into a joyfulromance! Provided by the Springer Nature SharedIt content-sharing initiative, Nature Metabolism (Nat Metab) Because selenium is an essential element, sodium selenite is an ingredient in dietary supplements such as multi-vitamin/mineral products, but supplements that provide only selenium use L-selenomethionine or a selenium-enriched yeast. In another process the reduction is done in concentrated hydrochloric acid or ferrous iron salts catalyzed by chloride ions as reductant. Xu, X. M. et al. #color(white)(aaaaaaaaaa)color(red)("reaction arrow")#, The balanced chemical equation looks like this, #2"Na"_ ((s)) + 2"HCl"_ ((aq)) -> 2"NaCl"_ ((aq)) + "H"_ (2(g))#, 52977 views It is actually quite simple - you neutralize it by turning it into salt water! Bersuker, K. et al. Sodium selenite is a precursor of Sec biosynthesis, and supplement of cells with Na 2 SeO 3 could significantly increases the Sec level in cells (Kryukov et al., 2003). This is discussed further below, but what follows here assumes that you have judged the class to be capable of doing this experiment using a burette with reasonable expectation of success. Let's think for a moment about how we would make salt water without acids and bases. For all panels, *p<0.05 (students two-tailed t test). BMC Plant Biology The volumes of acid and alkali solutions that react with each other can be measured by titration using a suitable indicator. Example: What is the formula of the compound formed between sodium (group 1) and selenium (group 16) sodium valency = group number = 1 selenium valency = 18 - group number = 2. Except where otherwise noted, data are given for materials in their, https://en.wikipedia.org/w/index.php?title=Sodium_selenide&oldid=1063435895, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 3 January 2022, at 02:12. Chemical formula HCl. Well meet the chemical Montagues and Capulets, select the finest candidate for the reaction of sodium hydroxide and hydrochloric acid, set off into space, visit the worlds finest restaurant, and ever so muchmore. Values are relative to the same cell lines expressing nontargeting (CTRL) guide (=1.0), (b) Light microscope images of MDAMB231 and MCF10A cells subjected to CTRL or SEPHS2 KO. HCl is in almost all cases already aqueous for common chemistry, mostly dissociated into $\ce{H^+} + \ce{Cl^-}$ because it is a strong acid, which means water is the primary solvent, not HCl. Sodium selenide Sodium selenite Molecular weight 188.94 221.15 124.94 172.94 Color/form White crystals Colorless crystals or white powder b Crystalline; turns red on exposure to air and deliquesces White tetragonal crystals Physical state Solid Solid Solid Solid Melting point No data No data >875 EC No data . Calculated pH values of common acids and bases for 1, 10, and 100mmol/L (valid for standard conditions at 25, 1atm; acidity constants are taken from here): The limited solubility of hydroxides is taken into account (as indicated by footnotes in the last column). Kim, J. Y. et al. National Center for Biotechnology Information. Biol. Extended Data Fig. Is it known that BQP is not contained within NP? This can be done by combining the acid with a base, such as sodium hydroxide (a strong base). Extended Data Fig. Burette stands and clamps are designed to prevent crushing of the burette by over-tightening, which may happen if standard jaw clamps are used. Food Addit. And now lets dive in even deeper, examining the reaction of sodium hydroxide and hydrochloric acid in the classification of chemicalreactions. Redox imbalance in cystine/glutamate transporter-deficient mice. Nature 575, 693698 (2019). Sodium selenide reacts with acids to produce toxic hydrogen selenide gas. Slowly add HCl to cold water until it reaches a 1:10 dilution of acid to water. Open Access A.N.M.-O. Open Access in equilibrium with solid phase Ba(OH)2:8H2O2, in equilibrium with solid phase Portlandite2, in equilibrium with solid phase Brucite2, in equilibrium with solid phase Calcite2, in equilibrium with solid phase Fe(OH)22, in equilibrium with solid phase Cd(OH)22, in equilibrium with solid phase Co(OH)22, in equilibrium with solid phase Zn(OH)2-c2, in equilibrium with solid phase Ni(OH)22, in equilibrium with solid phase Be(OH)22, in equilibrium with solid phase Cu(OH)22, in equilibrium with solid phase Pb(OH)22, in equilibrium with solid phase Cr(OH)3(a)2, in equilibrium with solid phase Hg(OH)22, Copyright 2012-2023 aqion. contact The micronutrient selenium is incorporated via the selenocysteine biosynthesis pathway into the rare amino acid selenocysteine, which is required in selenoproteins such as glutathione peroxidases and thioredoxin reductases1,2. The toxicities of mixtures of 50 M sodium selenide plus 20 or 40 M metal ions were compared. By using pH paper or a pH meter during the process, we can ensure that we end up with a neutral solution, which can be safely disposed of. Sheehan, T. M. & Gao, M. Simplified fluorometric assay of total selenium in plasma and urine. Use a model, feedback, reapply loop to develop students practical skills, Practical experiment where learners produce gold coins by electroplating a copper coin with zinc, includes follow-up worksheet. Let's say that in this experiment we were using 0.5 M HCl and 0.1 M NaOH. Selenide gas was formed by mixing sodium selenide, at a final 50 mM concentration, into 3.7% hydrochloric acid solution. Then, 20 mL of 0.15 M sodium . In these crystals, each cube face becomes a hollow, stepped pyramid shape. So if the Chemists intend to have dealings with them, they must protect themselves as best they can: they have no recourse but to work with them in a fume hood, and wear a lab coat, apron, gloves, special boots, and glasses or a protectiveshield. g, Immunoblots of GPX4, SEPHS2 and Hif1a in MDAMB231 cells subjected to hypoxia (1% O2) for 48hrs. The aggressive sodium hydroxide and hydrochloric acid interacted, and the result yielded usefulproducts. On this Wikipedia the language links are at the top of the page across from the article title. To calculate molarity, divide the number of moles by the volume. et al. Ingold, I. et al. - Definition, Causes & Facts, Magnetic Declination: Definition & Angles, Working Scholars Bringing Tuition-Free College to the Community. https://orcid.org. Handpicked Products Essential while Working from Home! Extended Data Fig. Filling the burette, measuring out the alkali into the flask, and titrating it until it is neutralised takes about 20 minutes, with false starts being likely for many groups. Naphthol | Structure, Solubility & Polarity, Chromic Acid Overview & Function| Liquid Chromic Acid Formula & Examples, Bond Enthalpy | Table, Equation & Calculations, How to Identify Chemicals in Solution: Test Methods & Materials, Using Sodium Hydroxide Solution to Identify Metal Ions. This work was supported by the Suh Kyungbae Foundation (SUHF) Young Investigator Award to D.K. e, Total thiol quantification of 24hr conditioned media from control and SLC3A2 KO U251 cells. f, Micrographs of serial human tumor sections stained with CD31 antibody and in situ hybridized with SEPHS2 RNA probe, showing vasculature. 10ae b, Percentages of Annexin V+/PI- and Annexin V+/PI+cells. Unit 2: CHEMICAL BONDING, APPLICATION OF CHEMICAL REACTIONS and ORGANIC CHEMISTRY, (j) titration as a method to prepare solutions of soluble salts and to determine relative and actual concentrations of solutions of acids/alkalis, Unit 1: THE LANGUAGE OF CHEMISTRY, STRUCTURE OF MATTER AND SIMPLE REACTIONS, 1.7 Simple equilibria and acid-base reactions, Improving our Classic chemistry demonstrations collection, How to help students develop their practical skills, Gold coins on a microscale | 1416 years, Practical potions microscale | 1114 years, Antibacterial properties of the halogens | 1418 years, Small (filter) funnel, about 4 cm diameter, Microscope or hand lens suitable for examining crystals in the crystallising dish. Can you write oxidation states with negative Roman numerals? Cell 172, 409422 e421 (2018). The concentration of the solution does not need to be made up to a high degree of accuracy, but should bereasonably close to the same concentration as the dilute hydrochloric acid, and less than 0.5 M. Dilute hydrochloric acid, HCl(aq) see CLEAPSSHazcardHC047a and CLEAPSSRecipe Book RB043. (b and c) Box plots of SEPHS2 mRNA expression levels in patient tumors and normal breast tissue. To calculate molarity, divide the number of moles by the volume. 3 Induction of cell death by SEPHS2 KO in cancer cells. ; NIH T32 CA130807-8 to M.E.S. copyright 2003-2023 Study.com. Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA, Anne E. Carlisle,Namgyu Lee,Asia N. Matthew-Onabanjo,Meghan E. Spears,Daniel Youkana,Mihir B. Doshi,Austin Peppers,Rui Li,Alexander B. Joseph,Karl Simin,Lihua Julie Zhu,Leslie M. Shaw&Dohoon Kim, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA, Environmental Testing and Research Laboratories, Leominster, MA, USA, You can also search for this author in Acidic Solutions Properties & Examples | What is an Acidic Solution? You are using a browser version with limited support for CSS. Producing a neutral solution free of indicator, should take no more than 10 minutes. 1. One of the most exciting and ambitious home-chemistry educational projects, It looks like you are visiting our site from, The reaction of sodium hydroxide and hydrochloric acid. In this case, it just so happens to also be table salt (NaCl). Catalysts are substances that speed up the pace (velocity) of a chemical reaction without being consumed or becoming part of the end product. Ciriello, G. et al. This is to avoid vulnerable and expensive glassware (the burette) being collected from an overcrowded central location. CAS NOTE: ALL NUMBERS IN FORMULAS SHOULD BE WRITTEN AS SUBSCRIPTS. Here, we show that selenophosphate synthetase 2 (SEPHS2), an enzyme in the selenocysteine biosynthesis pathway, is essential for survival of cancer, but not normal, cells. This is a resource from thePractical Chemistry project, developed by the Nuffield Foundation and the Royal Society of Chemistry. By thermal effect, it is exothermic. To understand the full extent of the tragedy, lets get better acquainted with them and examine the nature of sodium hydroxide and hydrochloric acid. Sodium hydroxide (NaOH) mixed with hydrochloric acid (HCl), a simple acid base reaction, results in the formation of salt and water. Q. Hydrochloric acid reacts with a metal X to form a gas Y which burns with a 'pop' sound. Sodium hydroselenide is a chemical compound, an inorganic salt; each unit consists of one sodium, one selenium, and one hydrogen atom. Med. Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase. Nature 520, 5762 (2015). Sodium selenate is leached in water and is reduced to sodium selenide, which is then oxidized by blowing in air through the solution. and P.L.G. Jiang, C., Wang, Z., Ganther, H. & Lu, J. a, Validation of SEPHS2 RNA probe by RNAscope in situ hybridization in MDA231 cell pellet block samples. You wonder how to properly dispose of the strong hydrochloric acid. Nat. HCl can also be neutralized with baking soda. In practice it does not matter if the end-point is overshot, even by several cubic centimetres, but the aim is to find the proportions for a roughly neutral solution. This inorganic compoundrelated article is a stub. d, Immunoblots of SLC3A2 in cells transduced as indicated e, Immunoblots of PSTK in cells transduced as indicated. This means that your reactants will be sodium metal and hydrochloric acid, since these are the substances that are being transformed to form salt and hydrogen gas. Styling contours by colour and by line thickness in QGIS. These reactions release heat into the surroundings, resulting in an increase in temperature. Wear proper protective equipment, such as gloves, safety glasses, and lab coat, to protect from splashes before beginning the neutralization process. Each activity contains comprehensive information for teachers and technicians, including full technical notes and step-by-step procedures. The right lower quadrant represents Annexin V positive and PI negative early dying cells. It is not the intention here to do quantitative measurements leading to calculations. By the number and state of the reactants and products, it is an exchange reaction. All other authors declare no competing interests. For all panels, the measure of center is mean. Sodium hydroselenide dissolves in water or ethanol. Free Radic. Well look at our planet from a distance. National Institutes of Health. We can evaporate the water off by slowly boiling the solution over a heat source (such as a Bunsen burner), which will leave us with salt crystals. Values are relative to the same cell lines expressing nontargeting guide (=1.0). The right upper quadrant represents Annexin V positive and PI positive late dying/dead cells. PLoS One 8, e54353 (2013). and D.K. And thus the two warring families ceased their aggressions and madepeace. In order to reach neutrality, we need to have the same number of moles of hydroxide (OH) as hydrogen ions (H). In humid air sodium hydroselenide is changed to sodium polyselenide and elemental selenium. Sodium selenide; Selenodisodium; Disodio selenide, Interesting Information Only Few People Knows, This system is delivered to you by Vietnamese students and teachers But it just so happened that the handsome Sodium Hydroxide, from the Alkali family, fell in love with the enchanting Hydrochloric Acid from the Acidfamily! This is a common acid-base reaction. 8 Reactive oxygen species production by excess selenium, and implications in SEPHS2 KO toxicity. Like sodium hydroxide, baking soda can also work to neutralize hydrochloric acid. Formula of sodium selenide = Na 2 Se. And now lets visit the best of restaurants you decide which! All samples were lysed between 7~8 days after viral transduction. And believe us, they wont say caviar, truffles, or parmesan, theyll say salt and water, as without these ingredients you cant prepare a single dish. Site design / logo 2023 Stack Exchange Inc; user contributions licensed under CC BY-SA. H2Se (Dihydrido selenium; Dihydrogen selenide; Hydrogen selenide; Selenium hydride; Dihydridoselenium), appearing at the end of the reaction. Try refreshing the page, or contact customer support. View all equations with Na2Se as reactant, I don't want to support website (close) - :(. Sodium Hydroxide Formula, Structure & Symbol | What is NaOH? We thank M. Green, E. Baehrecke, A. Mercurio, D. Sabatini, C. Haynes, D. Guertin, B. Bible, K. Krupczak, K. Luk, C. Brown, A. Jaferi and S. Deibler for advice, assistance and feedback. Evaporating the solution may take the rest of the lesson to the point at which the solution can be left to crystallise for the next lesson. Natl Acad. By the type of interacting substances, it is a neutralizationreaction. CAS 2 Further details of effects of SEPHS2 KO and overexpression in cells and in the MDA231 orthotopic xenograft. Identify those arcade games from a 1983 Brazilian music video. conceived the project; A.E.C., N.L. HCl | hydrogen chloride react with Na2Se | Sodium selenide; Selenodisodium; Disodio selenide produce NaCl | sodium chloride + H2Se | Dihydrido selenium; Dihydrogen selenide; Hydrogen selenide; Selenium hydride; Dihydridoselenium. However, it is also important to consider the number of hydrogen bonds formed between molecules, as you have already noted in your question. One such reaction occurs between hydrochloric acid (HCl) and sodium hydroxide (NaOH). Why must you use another 25 cm3of sodium hydroxide solution, rather than making your crystals from the solution in stage 1? sodium chloride, NaCl(aq) hydrogen gas, H2(g) This means that your reactants will be sodium metal and hydrochloric acid, since these are the substances that are being transformed to form salt and hydrogen gas. And thus, our love story has a happy ending: lovers from two hostile families have joined together inunity. PubMed To write a balanced chemical equation that describes this single replacement reaction, remember that, #overbrace("Na"_ ((s)) + "HCl"_ ((aq)))^(color(blue)("reactants")) -> overbrace("NaCl"_ ((aq)) + "H"_ (2(g)))^(color(darkgreen)("products"))# What are the chemical and physical characteristic of Na2Se (Sodium selenide; Selenodisodium; Disodio selenide)? J. Lets first visit the chemical laboratory. And its equation reads asfollows: Hydrochloric acid and sodium hydroxide interact, resulting in salt and a release ofheat. Nutr. You can help Wikipedia by expanding it. Get unlimited access to over 88,000 lessons. Once we are almost finished adding the 2.5 L of sodium hydroxide, we start checking the pH. Each product formed is harmless. Here you can find out more about thisdowry. Values are relative to the cells cultured in normoxic condition (20% O2), set at 1.0. d, Viability of control, SEPHS2, GPX4, and SEPSECS deficient MDAMB231 cells under nutrient starved conditions (10% growth media) for 48hr. What are the chemical and physical characteristic of HCl (hydrogen chloride)? Science 343, 8084 (2014). Extended Data Fig. That means you can actually reduce the concentration of insoluble salicylic acid by adding base, e.g. 4. . Tumor subtypes having over 2-fold SEPHS2 expression in tumor than normal and q-value less than 0.01 indicated with red. The acid and base react to form a salt and water. For instance, in a certain experiment there are 0.5M HCl and 0.1M NaOH. around the world. Titrating sodium hydroxide with hydrochloric acid | Experiment | RSC Education Use this class practical to explore titration, producing the salt sodium chloride with sodium hydroxide and hydrochloric acid. Jiang, L. et al. Number is an animal identifier number. Pure HCl under ambient conditions is actually a gas (thus certainly not a pure liquid solvent).